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Biotech / Medical : Incyte (INCY)
INCY 101.31-2.5%3:31 PM EST

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To: Biomaven who wrote (2655)5/11/2011 12:42:50 AM
From: software salesperson  Read Replies (1) of 3202
 
from 5/10 BofA presentation

rationale for rux pancreatic cancer trial:

1) animal models show heightened sensitivity to apoptosis from chemotherapeutics when JAK pathway is taken out at the same time

2) penetrate tumor

3) prevent severe cachexia development

it will be a P2b study that could be registrational

the endpoint will be overall survival

it will be for 2nd line

capecitabine + rux vs. capecitabine

sales
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