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Biotech / Medical : Incyte (INCY)
INCY 104.18+0.1%3:59 PM EST
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To: software salesperson who wrote (2712)12/14/2011 10:22:05 PM
From: scaram(o)uche   of 3202
 
It means that 050 is pissed out, rather than being processed by liver enzymes. The "cyp" liver enzymes are sometimes asked to do double duty, and you can change a drug's clearance profile if you're simultaneously taking a medication that uses the same enzyme. That is, Incyte is implying that other important medicines are cropping up that have liver clearance issues with tofacitinib.

Specifics, I know nada. I just did a BRIEF search, google and PubMed, and didn't find much of interest.
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