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To: The Ox who wrote (999)	6/21/2012 10:27:31 AM
From: The Ox	Read Replies (1) of 8239

8:00AM Chelsea Therapeutics reports combined Northera data from two Phase 3 trials confirm symptom improvement in patients with neurogenic OH ( CHTP) 1.31 : Co reports results from an integrated dataset of two phase 3 studies, Study 301 and Study 302, which showed that patients treated with Northera experienced improvements in their symptoms of Neurogenic Orthostatic Hypotension as measured by the Orthostatic Hypotension Questionnaire composite score and a number of individual symptoms, including dizziness. Additional data from co's integrated analysis showed that droxidopa-treated patients experienced improvements in their symptoms of Neurogenic OH as measured by the Orthostatic Hypotension Symptom Assessment score; 3 of the 6 items of the OHSA (dizziness, weakness, fatigue); the Orthostatic Hypotension Daily Activity Scale composite score; and all 4 individual items of the OHDAS Treatment with droxidopa showed low rates of supine hypertension.

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