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Biotech / Medical : XOMA. Bull or Bear?
XOMA 31.21-1.9%11:53 AM EST

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To: aknahow who wrote (4934)11/29/1997 2:17:00 PM
From: Andrew H  Read Replies (1) of 17367
 
Well, the comments about the 7 amputations are somewhat troubling. I agree that additional details from the company would be helpful.

Still it is better to live with an amputation than to die. Here are my first thoughts in regard to this. While the fact that 7 of 25 children had amputations will not help Xoma's stock price, my guess is that it no way alters the likely efficacy of the drug.

It is hard to imagine that doctors would suddenly start amputating more for those taking BPI in order to save lives than they would under other circumstances. It would seem that they would always amputate when they thought there was a reasonable expectation of helping chances of survivial. Of course any amputation is very unfortunate and moreso in the case of a child.

I agree that historical comparisons would be helpful. The amputations probably do mean that BPI is not a magic cure all, but that is really too much to hope for in meningococcemia.
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