SWOOP DOWN LIKE A GIANT CONDOR
To: Mike M who wrote (5060) |
2/13/2004 6:53:32 PM |
| From: StockDung | Respond to of 5510 |
| |
SWOOP DOWN LIKE A GIANT CONDOR
It's entirely possible that it could be
recalled one day! Think about it! That's never happened to a
homeopathic remedy...ever!
Think about how the media and Feds (FDA)
could swoop down on this like a Giant Condor. On and on and on.
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Zicam® Induced Anosmia
Bruce W. Jafek, MD
Miriam Linschoten, Ph. D.
Bruce W. Murrow, MD, Ph. D.
Denver, CO
Introduction: Zinc is extensively utilized throughout the body,
supporting the activity of approximately 100 enzymes, the im-
mune system, wound healing, the senses of taste and smell, and
DNAsynthesis. Zinc supports normal growth and development.
The deleterious effects of both deficiency and toxicity (acute and
chronic) are described. Beneficial zinc absorption takes place via
enteral, parenteral, or cutaneous routes. Direct application to the
olfactory epithelium, on the other hand, has long been known to
be toxic, producing anosmia. This toxicity is thought to be due to
the direct effect of the divalent zinc ions on olfactory receptor
cells. Apparently overlooking this toxicity, however, intranasal
Zicam® (zinc gluconate) has recently been recommended as a
treatment for the common cold.
Methods: We will present a series of patients with post- Zicam®
anosmia. The mechanism of drug toxicity will be analyzed.
Results: While interindividual variation in drug response and
drug toxicity is apparent, post- Zicam® anosmia appears to be
dose- related and permanent.
Conclusion: Zinc ions remain toxic to human olfactory epithe-
lium, and continued reports of total, probably irreversible,
anosmia, can be expected as long as intranasal zinc gluconate gel
(Zicam®) continues to be used. The recent extension of the use
of Zicam® to the pediatric age group is particularly alarming
since this group is less likely to be able to describe the anosmia.
Immediate discontinuation of the use of intranasal zinc recom-
mended.
"Those who do not learn from history are doomed to repeat it."
— George Santayana (1863- 1952), noted philosopher |
