Yet another article addressing combo cancer therapies including PVCT's PV-10 ........ (link provided by PVCT this morning)
http://www.pvct.com/news/CancerWatch-2012-September.pdf
Concluding paragraph ......
Locally or regionally advanced melanoma
tumors without metastatic disease
can be a severe problem for
patients and for surgeons, said Vernon
K. Sondak, MD, chair of the department
of cutaneous oncology at Moffit
Cancer Center, Tampa, FL, in an
interview. “The logical approach is a
localized one,” he said. But whereas
radiation would be the obvious solution
for many cancers, melanoma is
notoriously poorly responsive to radiation.
Fortunately, he said a number
of tools have come along to treat this
group of patients, some—like PV-10
and V-TEK, create an immune effect.
“If it’s shown that they are causing
local destruction of tumors and are
causing T-cell infiltrates, I’m interested
in seeing how I can take advantage
of that. If phase III trials confirm
their benefits,” he said further, “adding
systemic immunological therapies
like ipilimumab and PD-1 with intralesional
injection therapies would an
extremely logical combination.” |
