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Biotech / Medical : Provectus Pharmaceuticals Inc.
PVCT 0.0686-1.7%Nov 20 4:00 PM EST

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To: Howard Williams who wrote (11738)1/22/2013 11:31:09 AM
From: NTTG2 Recommendations  Read Replies (1) of 13111
 
Pretty much more of the same old story...

- still no evidence that RB selectively partitions into CA cells (nice cartoon, data would help)

- They really need to stop showing this combined treatment on remote tumor data as presented...at least normalize the numbers to the time zero values....the intrinsic data scatter (baseline of 8 to over 20...uummm...what are those units for?) is HUGE otherwise

- they continue to compare apples and aardvarks (where is the IT Actinomycin D, or 5-FU, or platinum, or..... comparator data?) Oral RB rather than IP RB?????? really...for a drug that is cleared by the liver in first pass metabolism, through a pathway that the company touts as part of their 'safety story' for???? Data geared to sell the story, not tell the story for sure

- Finally we get to a study that is reasonably controlled for IP and IT treatment with RB and temozolomide and...alas...no real differences over 14 days.

They do know how to do the right study, they just seem to work hard at avoiding it as much as possible
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