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Biotech / Medical : Provectus Pharmaceuticals Inc.
PVCT 0.06500.0%Nov 14 9:30 AM EST

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To: Howard Williams who wrote (12056)6/11/2013 9:08:05 AM
From: boomertree22 Recommendations

Recommended By
Howard Williams
Jack Russell

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Good paper. Highlights the importance of the Stage III trial protocol dosing determination in the success of treatment, particularly in patients with greater tumor burden and aggressive disease. Paper illustrates that PV-10 has systemic or bystander effect on untreated tumors, but immune response can't keep up with patients with heavy tumor burden and aggressive disease. Ideal dosing decision would allow more frequent dosing and injection of a greater number of tumors. This is supported by the impressive Phase II trial finding that "Among those patients who had all of their tumor burden treated, 54% had complete responses." I had not heard that finding before this paper.
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