Traumatic Brain Injury (TBI) and Anatabloc At GNC
The element Anatabine is the main element in the nutraceutical supplement Anatabloc sold at 4,000 GNC and online at www.anatabloc.com
Dr. Michael Mullan, president and CEO the Roskamp Institute noted that; “Both traumatic brain injury (TBI) and multiple sclerosis (MS) have in common massive brain inflammation. The reason anatabine looks so promising in both these conditions is likely because, as we have previously shown, it is a potent anti-inflammatory agent. Although anatabine’s anti-inflammatory activity may have different roles in each of these conditions the net result is to reduce the clinical and neuropathological consequences.”
TBI
The Promise of Anatabine in Anatabloc
David Loane, a scientist at the Center for Shock, Trauma, and Anesthesiology Research (STAR) at the University of Maryland, says new research suggests that TBI results in chronic microglia activation, which changes the brain’s white matter. “We’re beginning to see that microglia activation and neuroinflammation is a chronic pathology that’s associated with TBI,” he says. “It’s a progressive and chronic disorder that continues indefinitely after the initial traumatic insult.” Given that inflammatory pathways are so significantly affected, Fiona Crawford, a researcher at the Roskamp Institute, wondered if some of the long-term damage, particularly memory problems, could be avoided by using a compound that dampens the brain’s natural inflammatory response. She and her colleagues had already found evidence that anatabine, a dietary supplement found in tobacco leaves, tomatoes, and eggplant, was a powerful anti-inflammatory agent. https://www.dana.org/news/features/detail.aspx?id=40318
Anatabloc Inflammation Video
http://www.youtube.com/watch?v=AmC3Ths-Mt8
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Research Presented at Neuroscience 2012 Indicates Anatabine Supplementation is Potentially Helpful in Recovery from Traumatic Brain Injury
SEE http://tinyurl.com/chzskfl
GLEN ALLEN, Va., Oct. 15, 2012 /PRNewswire/ -- Star Scientific, Inc. (NASDAQ: STSI) through its wholly owned subsidiary, Rock Creek Pharmaceuticals Inc., reports that scientists from its research partner, the Roskamp Institute, presented new research yesterday and today indicating that supplementation with anatabine, the active ingredient in the Company's Anatabloc® dietary supplement, has the potential to alleviate the negative consequences of traumatic brain injury (TBI). These findings were presented during a press conference and also at a nanosymposium presentation at Neuroscience 2012, the 42nd annual meeting of the Society for Neuroscience, attended by more than 32,000 neuroscientists from around the world. Those scientists are gathering in New Orleans, Louisiana, this week to observe and participate in presentations relating to more than 16,000 new discoveries in science and health.
(Logo: http://photos.prnewswire.com/prnh/20120301/NE62741LOGO)
On Sunday morning, Dr. Fiona Crawford, Associate Director and Vice President of the Roskamp Institute, was one of four presenters participating in a press conference titled," 'Invisible' Wounds: From Soldiers to Citizens", which focused on traumatic brain injury research working to improve the lives of citizens and soldiers. In the press conference, Dr. Crawford described the Roskamp Institute's larger traumatic brain injury research program and the Institute's work investigating anatabine's effect in laboratory models of TBI.
On Monday morning, Dr. Scott Ferguson, also of the Roskamp Institute, presented these data in a presentation titled, "TBI-Induced Spatial Memory Loss is Averted by Treatment with the Dietary Supplement Anatabine". In this study, three groups of mice were studied: One group of TBI mice was treated with anatabine, while a second group of TBI mice was untreated. A third group was comprised of normal mice. The results of the study showed that the untreated TBI mice demonstrated memory impairment; whereas, the memory of anatabine treated TBI mice was the same as normal mice. The scientists at the Roskamp Institute hypothesize that the maintenance of normal memory in TBI mice treated with anatabine is due to an inhibition of inflammation. The presentation abstract notes: "Anatabine treatment appeared to completely prevent the loss of spatial memory retention following severe TBI."
Dr. Crawford stated, "Further study of this promising treatment is warranted and will include evaluation in a mild closed head injury model as well as assessment of long term outcome from injury." Dr. Michael Mullan, President and CEO of the Roskamp Institute, explained, "Dietary supplementation to prevent memory loss after head injury has a potentially rapid development path for human use." According to the Centers for Disease Control, 1.7 million people in the United States experience TBI each year, with 80,000 survivors suffering long-term disability.
In addition to the TBI research, the Roskamp Institute presented results of its research examining the potential benefit of anatabine for alleviating symptoms associated with Multiple Sclerosis and will present new research on anatabine's effect on Alzheimer's Disease at the conference. For more information about the TBI study and the MS study, visit the Roskamp Institute's website at: www.rfdn.org
Can Anatabloc Successfully Treat Alzheimer's?
Dr. Michael Mullan, M.D., Ph.D., President and CEO of the Roskamp Institute, commented: "We have known for a long time that Alzheimer's disease has a large inflammatory component. We also have observed the anti-inflammatory effects of anatabine (the active ingredient of Anatabloc) in laboratory tests which is why we anticipate evidence of anti-inflammatory effects in this population.”
Scientists Establish Link Between Inflammatory Process and Progression of Alzheimer's Disease
sciencedaily.com
What to do, to reduce the risk of Alzheimer's Disease? SEE http://lnkd.in/hte5Zk
Anatabine=Anatabloc supplement GNC
Brain inflammation Alzheimer http://bit.ly/Tk1Wxn
Dr. Michael Mullan, the CEO and President of the Roskamp Institute stated, “Anatabine continues to demonstrate widespread anti-inflammatory properties in a broad array of pre-clinical models. Given the commonality of inflammatory systems in rodents and humans, there’s much reason to expect that anatabine will demonstrate similar properties in humans. In fact, the team went on to demonstrate that in human blood inflamed with LPS, the presence of anatabine dramatically dampened the inflammatory response, a result also included in the paper.”
A New Look at Brain Inflammation in Alzheimer's
www.dana.org/news/features/detail.aspx?id=40308
Dr. Michael Mullan http://www.youtube.com/watch?v=NRyLA4uxpPE&feature=youtu.be
Anatabloc Video Summaries
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