Hi Rick-
I will have to think about this one for a few days, as I am in the midst of moving* to the Madison, WI area, also known as Madtown. lol. But I do think you are on the right track. One guess that I have for '093 is that it could also be a selective JAK2 for kidney disease(s), particularly nephropathy? This type of mechanism could be devoid of some or all of the hematological negative effects.
*My notes on various stocks are safely tucked away in a POD, the mechanism we are using for our moving of our household belongings. I have heard various success stories using PODs, and our 2 PODs arrived safely in WI with a minimum of disturbance after going to the storage site in Madison. Give me a week and I should be fully back online etc., unless Lake Mendota, north of the UW campus, takes away some/much of my free time for canoeing, kayaking and similar such water activities. Great fresh water fishing lake as well. The biotech scene here in Madison is pretty interesting, though much smaller that on either coast of course.
BJ |