Aaron,
I am invested in Vivus because for now I think that it has the best approved ED product on the market. Transurethral insertion is one thing - penile injection NO WAY! Viagra will be very big and greatly expand the ED market. It seems that it will not be as effective for those with physical causes vs psychologic so I think that there will be room for both. i have seen a low rate of vaginal irritation mentioned with MUSE but nothing like you speaker suggested and NO recommendation to use condomes. So I copied your post to VIVUS board and this is the reply from a knowledgable neonatologist who has an interest in muse and vivus.
Jim
To: James Baker (8 )
From: Cacaito Sunday, Dec 7 1997 7:44PM EST
Reply # of 12
James, Muse is prostaglandin E1, Cervical gels uses E2. There are no
repors of women problems, the FDA clear that before approval.
Prostaglandins are quikly metabolized to inert compounds locally, by the
time a man ejaculate it is mostly absorbed and changed into non active
compounds.
There is some concern about MCHM product is a gel to be applied to the
mucosa and/or skin of the penis, theoretically more chances of giving
women a side effect, but not the cramps and cervical stimulation that
are associated with PGE2, but redness and itching secondary to
vasodilation cause by PGE1 itself. This was reported in Muse users
female partners at about 5% in the main study (published in NEJM). It
was not establish to be directly due to the Muse use, just an
association. Post marketing there are no reports of female partners
problems in more than 300,000 patients.
The "blue pink purple" vision is a direct Viagra side effect(3% to 5%)
meaning the clear cause of it. If it will be a less or more serious
problem is still a quetion to be answered in the future.
Padma-Nathan recently in a Fox channel was talking about Viagra (I have
not confirmed this, I read it in the HVSF thread) and gave results of
40% to 80%, much restrained and less bullish than before when he was
only talking the higher number. Viagra, if approved, will take the mild
cases and the psychogenic ones, the rest is for Muse, and worst cases
will be for the injectables. |
