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Biotech / Medical : ARIAD Pharmaceuticals

ARIA 23.99

0.0%

Feb 17 4:00 PM EST

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To: Biomaven who wrote (2932)	11/3/2013 4:44:58 PM
From: GregorioAllegri	Read Replies (1) of 4474

That is what I would like to know as well. I think what jq1234 is telling us is that the FDA 48% number for the phase I is not cardio events, but is everyone who left the trial for drug intolerance for any reason in over the 3 years of the trial, including those who died for drug unrelated reasons or perhaps even from CML. If so, the FDA wording is worse than ambiguous, it reads like fear mongering - like someone with an agenda. Considering these were very sick people to begin with, considering that Bosulif has an 11 mo median time to progression, the fact that over half are still on ponatinib with complete remission after 2.7 years is a big time twist on what is in the FDA communique, and makes me think that I have been had. I just don't know by whom yet... ga

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