SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Provectus Pharmaceuticals Inc.
PVCT 0.06400.0%Nov 7 9:30 AM EST
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
From: Howard Williams1/25/2014 8:54:19 AM
1 Recommendation

Recommended By
Max Fletcher

   of 13111
 
Thanks to vorlon1966 on Yahoo and IV .... How the drug works
**************************************************************************
investorvillage.com

How the drug works

Cancer cells never get the signal to die like normal cells do...they just keep multiplying......something they do at a faster rate than normal cells which makes them starved for oxygen. Oxygen starved cells become anaerobic and thus puts them into acidosis (acidic). They change to live like this...makes them a mean tough cell. So their ph is below 7 while normal cells are around 7.2

The PVCT group decided to try to target cancer to take advantage of this difference. Why not others? For years we had squeeze bottle mustard but glass bottle ketchup until someone saw the answer that was right under their nose....But I digress...

For whatever reason the targeting of cancer was under everybody's nose. Then PVCT had a "Ureka!" moment....target the ph difference and so they set to work. They set down to design a small molecule to bounce off normal cells and go into the lower ph cancer cells. They put together different atoms on the computer and ran simulations based on the ionic properties that should work. When they found a candidate that worked in the simulation they realized it already existed as an eye dye...Rose Bengal. They filed the patents the very next day.

Now why does pv-10 kill cancer? Well, in every cell there is a sub cell that is called a lysosome. It is very acidic. It's normal job is to chop up bits food for the cell to use...like a stomach. When a cell had divided enough times the nucleus sends a signal out and tells the lysosome to self destruct...thus spilling out its very acidic contents and killing the cell from the inside out. Cancer cells never give that signal for self destruction. Here is where pv-10 comes in. Due to the molecule's design it is attracted to acidic (negative charge) cells. Once in the cell it gets absorbed into the lysosome to the point of rupture. Thus causing cell death. Since most cancers are acidic....pv-10 will work on most cancers while sparing normal cells.
In fact any excess is processed out of the body and into the bile in about an hour.

The very nature of how it targets and why its safe is basic chemistry. Other drugs are trying to induce the cell death signal or target receptors found on the cancer cells surface. None have done so without damaging some normal tissue.....thus side effects.

PV-10 kills cancer and spares normal tissue by a very simple process. The fact it is also a dye has nothing to do with nothing. Many other drugs came from dyes....look that up
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  

HomeMailHotSubjectMarksPeopleMarksKeepersSettings
Terms Of UseContact UsCopyright/IP PolicyPrivacy PolicyAbout UsFAQAdvertise on SI
© 2025 Knight Sac Media.  Data provided by Twelve Data, Alpha Vantage, and CityFALCON News