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Biotech / Medical : bluebird bio Inc.
BLUE 4.9700.0%Jun 2 5:00 PM EST

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To: tuck who wrote (72)5/23/2014 10:29:57 AM
From: idos  Read Replies (1) of 163
 
Just note that the clinical trial you linked to is the USA one (HGB-204) and the Cavazzana abs is from the French (HGB-205) study.

investor.bluebirdbio.com

There are some preclinical data on the improved vector such as here:

abstracts2view.com

Nothing worrying.
On VCN: it is believed that between 0.3 - 3 at release should be ok (not too high to minimize the risks of insertional oncogenesis) and it may decrease in time.
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