You've probably already seen this, not new, but wanted to park it.....
(pointer from Miguel Perales M.D. ?@DrMiguelPerales)
full text.....
ncbi.nlm.nih.gov
Combining a CD20 Chimeric Antigen Receptor and an Inducible Caspase 9 Suicide Switch to Improve the Efficacy and Safety of T Cell Adoptive Immunotherapy for Lymphoma
Lihua E. Budde,1,2,3 Carolina Berger,2 Yukang Lin,2 Jinjuan Wang,2 Xubin Lin,2 Shani E. Frayo,2 Shaunda A. Brouns,2 David M. Spencer,4,5 Brian G. Till,2,3 Michael C. Jensen,2,6 Stanley R. Riddell,2,3,7 and Oliver W. Press2,3,*
1Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, United States of America
2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
3Departments of Medicine and Bioengineering, University of Washington, Seattle, Washington, United States of America
4Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America
5Bellicum Pharmaceuticals, Inc., Houston, Texas, United States of America
6Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Washington, United States of America
7Institute for Advanced Study, Technical University of Munich, Munich, Germany
Saint Louis University School of Medicine, United States of America |
