I take it they are referring to the placebo patients IN the study (not sure why they gave a range for placebo while they give one number for the treated patients). Anyway, this following paragragh from the new release is very good............
The primary end-point evaluation of these trials showed that treatment with LIDAKOL resulted in a statistically significant reduction of the healing times of acute herpes episodes versus the placebo control. Contrasting with the 8 to 10 days normal duration of untreated herpes episodes, LIDAKOL-treated patients were healed in an average of 4.1 days from beginning-to-end of their outbreaks.
I take it that they are saying they reduced the episodes in half, or more. This would make it the top drug by far.
Also note that Lidak's studies defined time to healing from the prodrome phase to healing. Pencicilovir was vesicle stage (skipping the prodrome, erythema, and papule stages), //So If you are going to compare the 2 studies, you need to compare each drug to the respective placebo in that study, NOT Directly to each other So to correct for the method of study, Penciclovir would reduce the outbreak to around 7 days, while Lidakol reduces it to 4 days.
Think I got that right. OK, so if it drops on this news, then I add more, if not, I already have enough. |