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Biotech / Medical : ARIAD Pharmaceuticals

ARIA 23.99

0.0%

Feb 17 4:00 PM EST

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To: kenyonn who wrote (4043)	12/14/2015 2:11:21 PM
From: Biomaven	of 4474

>> But won't those second-line failures eventually become pona patients anyway, due to the lack of options? Yes, but that takes a long time, and they are sicker when they get there, so time-on-drug is less. >>Doctors are going to figure out that when most patients fail on nilotinib, it doesn't work to go to dasatinib (or vice versa)--they're better off going to pona. Much better to have a trial to actually demonstrate that. >>they can beat nilotinib in efficacy and at least come out comparable in safety at these lower doses. One year safety is not enough to beat nilotinib, even if they show somewhat better efficacy.

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