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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST
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civic08801
To: jaybe who wrote (4070)12/22/2015 10:29:00 AM
From: mulanoon20071 Recommendation   of 4474
 
I certainly give credence to your opinion that PON might have advantages over ABL-001+NIL in IMA-R/R pts. Although I think the Haematologica report is more important than what meets the eye (i.e. it might not be a case of getting lucky with a handful of patients), the weight of NVS will keep the pressure on PON through aggressive trial execution and thought leader support. FWIW i think the 2L trial of PON is sensible because not only are =/>2% of pts each year falling into the IMA R/R category (i.e. =/>2k/year in the USA) but because of the drive to reach MR4.5 for drug cessation; tea leaves suggest that PON is likely to be more effective than NIL, DAS and BOS.
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