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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST
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To: tktom who wrote (4116)2/2/2016 12:54:31 PM
From: Biomaven   of 4474
 
>>'788 is targeting two mutations, EGFR and HER2, driven by exon 20 insertion mutations, doesn't that reduce the chances of early approval after a phase 2

Can't tell much until we see the preclinical data.

For '113, there was a significant difference in potency between ALK and EGFR - something I pointed out as soon as they disclosed it.

Resistant EGFR is a tougher target clinically than ALK,. likely because there are multiple modes of resistance.

nature.com
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