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Biotech / Medical : XOMA. Bull or Bear?

XOMA 32.93

+2.9%

3:59 PM EST

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To: nestegg who wrote (5193)	12/28/1997 11:46:00 AM
From: aknahow	Read Replies (3) of 17367

nestegg, remined me of a point from P I/II trial of 26 patients. BPI was not administered until patients were at 8 or higher on Glasgow scale. The average on this scale which goes up to 15 was 12 at the time of giving BPI. So even though given late in the open trials appeared to produce results. It is my understanding, from Biostock 1, who makes interesting informed post at aol, that P III also requires patients to be at 8 or higher on the scale for P III also. Must say I do not understand why the need to wait so long but if BPI worked in the open trial and the results were not a statistical fluke then one ends up believing thre is no reason it woul have stopped working in the blind trials. Also as a non professional in this field it would seem that in real life if approve for use BPI would be given early on without waiting for anyone to move to a higher level on the Glasgow scale and also closer to the time antibiotics were first administered. This would seem to be logical and IMO would seem to gve the sick kids a beter chance for survival. What am I missing here?

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