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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

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From: jaybe4/26/2016 8:46:44 PM
3 Recommendations

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Univ. Colorado now recruiting for AP32788...

Should start to see quite a bit of buzz from KOL's on this trial, which I estimate will complete enrollment by end of year (105 pts. out of 6,000 US incident pool). Looks like each cohort could lead to a separate pivotal trial in 2018. With activity against all EGFR mutations Cohort 4 could see upside in EGFR 2L in T790m-negative patients (45% of 2L), a relatively underserved population. Disappointing to see at AACR that Cohort 2 (Her2) will require higher (2-3X) dose, safety profile permitting.

clinicaltrials.gov
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