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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

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To: Biomaven who wrote (4325)6/23/2016 9:55:19 PM
From: jaybe   of 4474
 
Maybe they tried and were met with a different form of resistance...in HB. In any case this research corroborates FGFR/FRS2 and stat3 as promoters of MEK resistance in KRASm cancers, and ponatinib's ability to inhibit both, synergistically. This is likely an outcome of the first phase of the Lung Cancer Dream Team, supported by ACS and SU2C, as a few authors are members, announced in 2015.

"First, the researchers will identify the most effective therapies for targeting KRAS and other related biological pathways. Second, they will develop approaches to exploit the immune system for the treatment of KRAS-mutant lung cancers. Third, they will integrate targeted therapies with immunotherapies as a novel combined approach to treatment of KRAS-mutant lung cancer."

standup2cancer.org

cancer.org
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