SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
To: jesspro who wrote (4352)8/3/2016 10:56:01 PM
From: jaybe   of 4474
 
The appeal resulted in ALTA-1L, a potential frontline approval on only 270 patients (135 on briga). The sort of approval you're suggesting is seen only in diseases with NO available options, even chemo here counts as a viable alternative. What we don't know is what magnitude of benefit in mPFS over criz at interim (50% and 75% of events) could trigger early termination of the trial.
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext