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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ)
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To: blankmind who wrote (4267)1/4/1998 10:53:00 AM
From: Zebra 365  Read Replies (4) of 23519
 
To Cacaito,

First call has a consensus estimate of 0.18 for Q4 of 1997 (this is on their site through AOL right now with a 12/29/97 date), by my math this is 0.18 + 0.86 = $1.04 per share for 1997 earnings. Do you have a more recent First Call estimate of 0.04 for Q4 of 1997?

To All:

Prazosin is an alpha-blocker sold as an oral drug under the trade name Minipres for hypertension and for prostate enlargement. (don't get confused here, the prostate and impotence are not related) Alpha blockers are vasodilators (the active ingredient in Vasomax is phentolamine, an alpha-blocker) which work in a different way than PGE-1 (alprostadil, the current MUSE drug). The combination of alprostadil and prazosin would be expected to have higher efficacy than alprostadil alone. The use of a drug, prazosin, that already FDA approved and is being prescribed for other indications, would greatly speed the FDA approval process for a new use as initial trials for safety data and side effects can be greatly reduced.

If the Phosphodiesterase blocker effect (Viagra) is more potent than alprostadil, there is nothing to prevent Vivus from adding a similar drug to a MUSE system for greater effect locally and less systemic side effect. Remember, it is the delivery system, not the drug that makes VVUS unique.

Zebra
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