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Biotech / Medical : Lidak Pharm. [LDAKA]

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To: Henry Niman who wrote (796)	1/5/1998 10:49:00 AM
From: John Zwiener	Read Replies (1) of 1115

I agree Henry. From the press releases, we have been led to believe that lidakol is 2 days better than placebo (at worst, and 4-6 days better, at best), and as good as acyclivir cream (also 2 days better than placebo). But this would give us a better p value. They imply that the placebo is 8-10 days by repeating the typical outbreak timeframe., but then you would get a great p value. Also I begin to wonder if BMY really did request that the numbers be withheld. One independent source is the Yamanuchi study that claim statistical comparability to acyclivir cream, but again no numbers. What would be the reverse statistical analysis of 750 patients with a p value of 0,035 and the treated group shows 4.1 days?

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