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Biotech / Medical : Juno Therapeutics Inc. (JUNO)
JUNO 86.960.0%Mar 6 4:00 PM EST

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To: Biotech Jim who wrote (57)3/2/2017 8:16:00 AM
From: Biotech Jim  Read Replies (1) of 84
 
Trying to pick up shares pre-market, but no many sellers.

Very interesting conf call. Lots going on.

Three keys to CRS and tox with JCAR017 (NHL and CLL could be first approvals, pretty good data with JCAR017):

Extent of early T cell clonal expansion due to 3 factors (extensively explored), and are directly causative to side effects of CRS, neurotox, and cerebral edema.

1. Treatments prior to cell infusion
2. Potential patient specific factors
2. Engineered construct and specific transduced T cell characteristics, ie product characteristics.

I am trying to buy some more JUNO this am, my orders are hidden but they are lower than current bids.
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