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Biotech / Medical : Regeneron Pharmaceuticals

REGN 755.90

+2.6%

Nov 21 4:00 PM EST

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To: Biotech Jim who wrote (2109)	5/4/2017 4:36:34 PM
From: Miljenko Zuanic	of 3559

CC transcript: seekingalpha.com <I'd like to spend a few moments focusing on findings from the long-term follow-up of our Phase 3 VIEW 1 study of EYLEA in patients with wet AMD, which were recently published in Ophthalmology Retina. As background, existing long-term data with other anti-VEGF agents, most notably from the government-sponsored CATT study, have shown that early visual gains obtained with anti-VEGF agents were not maintained over time. In fact, by the fifth year, patient had lost, on average, over three letters compared to their original baseline. Over 20% of patients have progressed to become legally blind by year five.....In marked contrast to the CATT study, long-term follow-up data from the VIEW 1 study, where patients who were treated with fixed interval EYLEA dosing and received EYLEA on average every 12 weeks in year 2 and every 8 weeks in year 3 and 4 showed that the vision gains observed at the end of the first year were on average largely maintained at 4 years.>

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