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Biotech / Medical : Regeneron Pharmaceuticals
REGN 755.75+2.5%3:59 PM EST
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To: Felix B who wrote (2143)6/20/2017 3:46:14 PM
From: Miljenko Zuanic  Read Replies (1) of 3559
 
ARVO 2017: arvo.org
P# A0087.....overal, ~50% pts were on > or = Q12W,

second year of View1/2, 40-50% were on Q12W: <<Conclusions: A numerically higher proportion of patients treated with IAI received injections at =q12 week intervals compared to ranibizumab from week 52 to 96. Visual acuity gains achieved at week 52 were largely maintained through week 96 in both subgroups. These data indicate that many patients maintained their visual and anatomic improvements with dosing at =q12-week intervals following fixed dosing during the first year>>

while here is mentioned only 30% (which is wrong, IMO):https://seekingalpha.com/article/4082631-brolucizumab-provides-comfort-novartis

Trial Protocol Criteria to hold Q12W regimen may be different between this two drug trials???
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