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Biotech / Medical : Regeneron Pharmaceuticals

REGN 737.00

+4.8%

Nov 20 3:59 PM EST

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From: Miljenko Zuanic	11/29/2017 1:25:40 PM
	Read Replies (1) of 3559

REGN1979 (this Abs is indeed from year 1979...), from ASH: <After observing rapid clearance, the dosing regimen was changed, and trough REGN1979 concentrations in serum became measurable during qw and q2w dosing and in higher dose groups. Ctrough levels of 350 mcg/L were noted in the 7 mg cohort, close to the level observed after a 0.1 mg/kg single dose in a murine tumor model. In this animal model, tumor control was observed after a 0.4 mg/kg single dose at exposures that were 2-fold (Cmax, Cav and AUC) to 4-fold (Ctrough) higher than those observed in the 7 mg cohort in patients; therefore further dose escalation continues.> Where is ADVANCE science (from start) here???? So far, their human/humanized Abs are nothing more than simple CRAP! They should fund "CRAPPY SCIENCE" as well, they are obvious LEADER here!

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