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Politics : View from the Center and Left

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To: koan who wrote (376420)7/10/2018 1:10:58 PM
From: Wharf Rat  Read Replies (1) of 542905
 
"why did Obama appoint a man of god as his science adviser??"

Cuz, on the eighth day, God told him, "I give you some of the keys to life, my child. Be fruitful and multiply, or at least become a government bureaucrat, which will make koan whine."

Francis Sellers Collins (born April 14, 1950) is an American physician- geneticist who discovered the genes associated with a number of diseases and led the Human Genome Project.

At Yale, Collins worked under the direction of Sherman Weissman, and in 1984 the two published a paper, "Directional Cloning of DNA Fragments at a Large distance From an Initial Probe: a Circularization Method". [5] The method described was named chromosome jumping, to emphasize the contrast with an older and much more time-consuming method of copying DNA fragments called chromosome walking. [6]

Collins joined the University of Michigan faculty in 1984, rising to the rank of professor in internal medicine and human genetics. His gene-hunting approach, which he named " positional cloning", [7] [8] developed into a powerful [9] component of modern molecular genetics.

Several scientific teams worked in the 1970s and 1980s to identify genes and their loci as a cause of cystic fibrosis. Progress was modest until 1985, when Lap-Chee Tsui and colleagues at Toronto's Hospital for Sick Children identified the locus for the gene. [10] It was then determined that a shortcut was needed to speed the process of identification, so Tsui contacted Collins, who agreed to collaborate with the Toronto team and share his chromosome-jumping technique. The gene was identified in June 1989, [11] [12] and the results were published in the journal Science on September 8, 1989. [13] This identification was followed by other genetic discoveries made by Collins and a variety of collaborators. They included isolation of the genes for Huntington's disease, [14] neurofibromatosis, [15] [16] multiple endocrine neoplasia type 1, [17] inv(16) AML [18] and Hutchinson–Gilford progeria syndrome. [19]

en.wikipedia.org
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