Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 199.07

-3.4%

3:59 PM EST

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To: Andrew H who wrote (13313)	1/14/1998 7:19:00 PM
From: Henry Niman	Read Replies (2) of 32384

Andy, I think that the type of activity is different for different diseases. The LGND initial data on lung cancer show stabilization of disease. In contrast, complete remisions were seen in lymphomas like CTCL and APL. I'm not sure about the activity in advanced solid tumors. The retinoids and rexinoids may have applications which fall short of irradication of the disease, but still have utility for treatment to stabilze the disease or ease pain but not "cure" the patients or put them in remission. Thus the compounds could have applications for many malignancies, but not produce remissions in solid tumors.

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