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To: Neeka who wrote (321)10/4/2018 6:45:31 PM
From: Alan Smithee  Read Replies (1) of 678
 
Use in biochemical warfareOne example of the powerful biological attributes of lectins is the biochemical warfare agent ricin. The protein ricin is isolated from seeds of the castor oil plant and comprises two protein domains. Abrin from the jequirity pea is similar:

  • One domain is a lectin that binds cell surface galactosyl residues and enables the protein to enter cells
  • The second domain is an N- glycosidase that cleaves nucleobases from ribosomal RNA, resulting in inhibition of protein synthesis and cell death.
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