All right Keith, ( can I cal you Keith? fell free to call me TA, gg ).
I will skip the general medical exam ( so we won't bore the audience, gg, and save time ) and try and achieve the same in a round about
fashion: Here are the questions:( first of medical natue, and then investing type).
A 65 yo W/M takes 1 Vasomax pill for ED.He is 6 ft 2 inches and is overweight at 250 lbs. Please show me the exact calculations you would use, and the results, to tell me:
- what is his total body water?
-what is his ideal body weight?
-how many liters of fluid are in his intravascular compartment and
how many in his interstitial compartment?
-what will the final concentration of phentolamine be in his serum
at 1/4, 1/2, 1 , 2, and 3 hours after ingestion.
-what is the final concentration be in the corpus cavernosum?
-what will the drop in his Blood Pressure ( systolic, diastolic,
lying and standing (are there +orthostatics ?)
be at the time his penile artery is vasodilated? )
-what is the t 1/2 of serum phentolamine?
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Investment questions: why are we hearing just now of a buccal admininstration of Vasomax and not before?
-Mucosaly absorbed vasodilators are fairly dfangerous because of the " rush" of drug in your system: that is why Pfizer's subling Procardia has been taken off. How is Phentolam different than Procardia? You are talking about an effect within 10-20 min.
Thanx
TA |
