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Biotech / Medical : Madrigal Pharmaceuticals

MDGL 418.90

-2.0%

Oct 31 9:30 AM EDT

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To: Miljenko Zuanic who wrote (125)	9/26/2019 11:29:28 AM
From: Miljenko Zuanic	Read Replies (1) of 138

OT: GLMD Aramchol p3/4 trial design similar to MGL-3196, but with FREEDOM to have other (I guess GLP-1 included) anti-diabetic medications at STABLE dose (and no pre-screen weight loss of >5%): Weight loss of more than 5% within 3 months prior to screeningHistory of bariatric surgery within 5 years of liver biopsy or planned surgery for weight reductionTreatment with drugs that may cause NAFLD within 12 months prior to liver biopsyTreatment with some anti-diabetic medications; Unless started prior to biopsy (timeframe depending on drug) and stable clinicaltrials.gov PS: Disclosure (I have LARGE GLMD position, which I may unload at any time..without on-time notice...)

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