MISCELLANEOUS MEDICAL/INVESTMENT INFO FOR NEW VIVUS INVESTORS;
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It's ok, VVUS, we all gotta be 40 someday.
Yes, and even more.
Frostman Oct 3 1997 : #531
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Vivus intraday chart
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Medical Articles on Vivus/Muse:
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1 )Alprostadil/Muse/Vivus
Treatment of men with erectile dysfunction with transurethral
alprostadil Padma Nathan H, Hellstrom WJG, Kuiser FE, Labasky, Tom
Lue,Nolten,Norwood,Peterson, Shabsigh,Tam, V.Place,Gesudheit,and 90
other collaborators, for the MUSE study group.
( New England Journal of Medicine, Jan. 1997; 336: 1-7 )
Alprostadil was delivered transurethrally in a double -blind
placebo-controlled study of 1511 men, 27 to 88 years of ag, who had
CHRONIC erectile dysfunction.The men were first tested in the clinic
with up to four doses of the drug (125,250,500,and 1000 mcg); those who
had sufficient responseswere randomly assigned to treatment with either
the effective dose of Alprostadil or placebo for three months at home.
RESULTS ; During in- clinic testing, 996 men ( 65.9% ) had erections
sufficient for intercourse.Of these men, 961 reported the results of at
least one home treatment;. Of these996 men ( 65.9 % )had a erectile
response satisfactory for intercourse
and were subsequently entered into a placebo controlled double-blind
trial: 461 received Alprostadil and 500 received placebo.Of the 461
receiving Alprostadil 299 had intercourse at least once( 64.9 % ), as
compared to 93 of the 500 who received placebo ( 18.6 %, p<0.001 ) ). On
average 7 of 10 men who received Alprostadil were followed by
intercourse in men responsive to treatment.
The efficacy of Alprostadil was similar regardless of age or the cause
of erectile dysfunction, including vascular disease, diabetes, surgery
and trauma ( p<0.001 for all comparisons with placebo ) .
10.8% of patients suffered from penile pain but this rarely resulted in
discontinuing treatment. Hypotension occurred in the clinic in 3.3 % of
men receiving Alprostadil.Hypotension- related symptoms were uncommon at
home.No men had priapism or penile fibrosis.
( from the Departments of Urology of:
Univ of Southern California;The Mayo Clinic ; Tulane Univ Med Center;St
Louis Univ;Univ of Utah;Univ of Calif; Peachwood Medical
Group,Clovis,Calif.,Univ of Wiconsin;Univ of Columbia,
Columbia-Presbyterian Hospital;)
( over 100 Urologists participated in the study and are listed in the
Apendix of the article).
This is an important paper with large numbers of patients in a well
organised study.
The response rates appear surprisingly good in patients with
vasculogenic impotence according to this study.
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2 )Alprostadil/Muse/Vivus after radical prostatectomy
pslgroup.com
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3 )Alprostadil/Muse/ Vivus in Diabetics, one of the largest causes of
impotence:
vivus.com
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4 )Another study on the excellent safety of intravenous ( in the
peripheral
vein by drip, and then by local intracavernous injections ) of
Alprostadil in the last, Oct 97 issue of ther Journal of
Urology,Vol158,1403-1497;
PHARMACOKINETICS OF PROSTAGLANDIN E1 AND IT'S MAINMETABOLITES AFTER
INTRACAVERNOUS INJECTION AND SHORT - TERM INFUSION OF PROSTAGLANDIN E1
IN PATIENTS WITH ERECTILE DYSFUNCTION:
BY Willi Cawelo,Horst Schweer, Bruno Dietrich, Hannsjofg WIlhelm,
Seyberth,Albrecht et al:
From the Univ of Marbufg, Ulm, Germany:
www3.techstocks.com
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| INVESTMENT UPDATE ON VIVUS |
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Vivus chart ( Brian Malloy,post #514 ).
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- Options page for VVUS:
-From: Navigator One Reply #391
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- Check out Vvius 2nd opinion site;( Dr. Bond, post #207 ):
etrade.stkwtch.com
-Vivus patent by Gene Voss, MD.-
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