| | | Just saw in in-tray
On Apr 14, 2020, at 6:32 PM, __________ wrote:
FYI—see the video and then check out R’s responses below
Still may need a ventilator but definitely used a different way than they have been using it
From: R
Subject: Re: (7) FROM NYC ICU: DOES COVID-19 REALLY CAUSE ARDS??!! - YouTube
Date: April 14, 2020 at 8:19:51 AM PDT
One possible treatment here would be to try the drugs that one uses to acclimate prior to moving to high altitudes.
I believe these are carbonic anhydrase inhibitors. They are all generic. This could be given to patients at earlier stages of disease.
Have you heard any market buzz about this?
R
On Mon, Apr 13, 2020, 22:46 R wrote:
Thanks...I have been aware of this finding for about 10 days based on findings of Chinese and American docs.
The disease radiologically looks like HAPE (high altitude pulmonary edema). This is not my area of expertise, but it seems to be more a pathophysiological problem with vasocobstriction of the blood vessels in the lungs that exchange oxygen rather than primary inflammation and thickening of the wall of the air sacs as seen with ARDS.
High pressure ventilation probably serves to further exacerbate the problem by damaging the air sacs and actually causing ARDS.
One solution suggested is to ventilate at lower pressure possible with higher oxygen concentrations. I thought that this was more widely understood by now. Since this video was recorded a week ago, I hope that this new theory has begun to change the treatment regimens.
Since this is primarily a disease of the lung vasculature, it is not surprising that both smokers and people with hypertension are at higher risk of death.
I wasn't sure if what I had read was true in most patients, but this doctor seems to validate that this happens more often than not in very sick patients.
On Mon, Apr 13, 2020, 21:33 ______ wrote:
Interesting take from a guy on the front line
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