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Strategies & Market Trends : 2026 TeoTwawKi ... 2032 Darkest Interregnum

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To: carranza2 who wrote (157564)	5/7/2020 8:53:51 AM
From: carranza2	1 Recommendation of 217544

More re: ammonium chloride and corona viruses (and why I take a small dose of it every day along with zinc and home-brewed quinine tea). Of these, zinc and ammonium chloride are the most expensive, at about $0.25USD per pill. I obtained cinchona bark at $1.50 per 1/2 oz. I dare anyone here to find ammonium chloride mentioned in any public medical forum as a possible therapeutic agent. If it’s cheap and potentially effective, fuggedabouit. We need remdisivir at $1000 a pop, not HCQ or NH4Cl. Where have we gone wrong.....when we pay attention to the men and women in long white coats, when we assume without supporting proof that they are all credible, altruistic, etc. It’s always about the mooolah. Always. virologyj.biomedcentral.com Ammonium chloride inhibits SARS-CoV infection of Vero E6 cellsSince chloroquine inhibited SARS-CoV infection when added before or after infection, we hypothesized that another common lysosomotropic agent, NH4Cl, might also function in a similar manner. Ammonium chloride has been widely used in studies addressing endosome-mediated virus entry. Coincidently, NH4Cl was recently shown to reduce the transduction of pseudotype viruses decorated with SARS-CoV spike protein [ 17, 18]. In an attempt to examine if NH4Cl functions similarly to chloroquine, we performed infection analyses in Vero E6 cells before (Fig. 4A) and after (Fig. 4B) they were treated with various concentrations of NH4Cl. In both cases, we observed a 93–99% inhibition with NH4Cl at = 5 mM. These data indicated that NH4Cl (= 5 mM) and chloroquine (= 10 µM) are very effective in reducing SARS-CoV infection. These results suggest that effects of chloroquine and NH4Cl in controlling SARS CoV infection and spread might be mediated by similar mechanism(s

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