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Biotech / Medical : Eli Lilly
LLY 1,057+1.5%3:59 PM EST

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From: Moonray6/18/2020 10:51:48 AM
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Lilly commences Phase III trial of baricitinib to treat Covid-19

Eli Lilly has started patient enrolment for a Phase III clinical trial
of baricitinib to treat adults hospitalised due to Covid-19 infection.

The Phase III trial will enrol approximately 400 patients across
the US, Europe and Latin America. It will recruit patients who
do not require invasive mechanical ventilation at the time of
entering the study.

Trial participants will be given 4mg baricitinib daily or placebo
for up to 14 days or until discharge from the hospital.

The primary endpoint of the trial is the proportion of patients who
die or need non-invasive ventilation/high-flow oxygen or invasive
mechanical ventilation by day 28.

Key secondary outcomes include clinical improvement at different
time points, time to recovery, duration of hospitalisation, ventilator-
free days, and mortality over a 28-day period.

More at: Lilly commences Phase III trial of baricitinib to treat Covid-19

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