Ivermectin - in vitro studies look good. And the other thing, some reports of personal experience using it - looks good too. I’m not aware of any clinical studies. So, if I were the patient, I’d go with HCQ. Or, if I took HCQ and there would be no response. Or, if I took HCQ as prevention - and would get sick anyway (in which case I’d have meaningful levels of HCQ in my bloodstream, and getting sick would look a lot like treatment failure).
“Evidence based medicine”.... There is always a human element. Read that Fauci - while studying Remdesivir - didn’t reach the outcome he expected, and simply changed the target - to fit the outcome. The medication shortened Hospital stay - and they decided that it’s going to be the target. It didn’t reduce overall mortality among patients - so, screw it, they just stopped thinking of it as the target.
Or, like that recent study in NEJM, done in Brazil — they couldn’t find enough patients who haven’t taken HCQ — AND just went ahead, and included all those who haven’t taken HCQ in the last 24 hours. Considering that the half life of HCQ is a month, maybe longer — this was a huge freaking joke. Don’t know about Brazil, but in the US every participant who got overdosed on HCQ has a great case of malpractice - and there were some who suffered side effects and as I recall, died.
Corruption. To paraphrase Stalin, it’s not the facts, it’s who interprets them. |