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Dr. Dennis Lo

Breakthrough Prize


Dennis Lo, a researcher at the Chinese University of Hong Kong, was awarded the $3 million prize for his discovery that the DNA of a fetus is present in a pregnant mother’s blood plasma in quantities that make it possible to create better tests for fetal genetic characteristics. This information in turn can help prepare doctors for any special needs or treatment that a child might need after birth. His first such discovery was in 1989, when he was successfully able to demonstrate the presence of a fetus’ Y chromosome in the mother’s blood. By 2008, he’d developed a non-invasive test for Down syndrome and in 2010 he was able to sequence the entire genome of a fetus. He’s now working on taking this approach of DNA screening to other applications, such as testing for cancer.
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