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Politics : Politics for Pros- moderated
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To: D. Long who wrote (727506)10/2/2020 9:12:33 PM
From: t4texas1 Recommendation

Recommended By
kech

   of 794329
 
i think the real reason (other than just precautionary in case covid creates a sudden trump change) for the hospital stay is to administer remdesivir. at this time remdesivir is only dosed with an IV drip, and that is dosed likely over about a 5 day course. the first dose is 200 mg rdv. the next days are 100 mg. at least that is what people have been getting. the fact that he was dosed with the monoclonal antibody cocktail was to inject some antibodies that are supposed to attack the virus load and reduce it. we all have various antibodies in our blood stream, and remdesivir does not cause problems with them. since trump has symptoms of covid, his own antibodies are not doing enough, and remdesivir at this early stage (we assume it is early stage covid infection) will interact with the virus reproduction and essentially kill the virus without interfering with the monoclonal antibodies that are in the blood stream. so that is my reasoning for the hospital trip of a few days. let's call the treatment belt and suspenders -- like in once upon a time in the west.

i know gilead has been doing trials of an inhaled remdesivir using a nebulizer. it goes straight into the lungs via breathing in the remdesivir mist through the mouth with a mesh nebulizer. i have included one of the government's links to one of the trials that it says are going on in bakersfield, west palm beach, and dallas. from start to finish each patient only needs 5 days, and it is for people who are Not in the hospital. you can read all kinds of details in this study detail tab. if you are interested and want more details, click on the tabular view tab. of course the inhaled rdv trials use much lower doses of rdv, because with the inhaled version it goes straight into the lungs. you can see in the link they should be finished with this double blind trial with 282 symptomatic covid patients who were not in the hospital. we should be hearing something soon, because even in the document (updated september 21) it says the primary completion date is october 2020. i am sure gilead has the data it needs to decide if the stuff works or not, and i assume something will leak sometime soon, especially if gilead starts talking to the fda about some of the results. i have a video of one brand of mesh nebulizer with a user using one that i can post if someone wants more details about these things.

clinicaltrials.gov
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