SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Ligand (LGND) Breakout!
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
To: medsunman who wrote (13965)1/30/1998 3:24:00 PM
From: Henry Niman  Read Replies (2) of 32384
 
medsunman, After reading the AP report, I realized that the baldness gene discovery may be more impotant to LGND than I thought. When I read about trying to use the gene to restore hair, I thought that the researchers were taking a rather narrow approach. Since there was a structural relationship between the hairless gene and the estrogen or androgen receptors, then related hormones could be just the right medicine. There have already been reports of topical applications of estrogens restoring hair in mice and they could be cross reacting with the hairless gene product (or another related zinc finger transcription factor).

Thus the find may speed development of estrogens (or anti-androgens). As you know, LGND has extensive programs in both areas, and using the hairless gene product (receptor) as a screening vehicle, may yield some fast and exciting results.
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  

HomeMailHotSubjectMarksPeopleMarksKeepersSettings
Terms Of UseContact UsCopyright/IP PolicyPrivacy PolicyAbout UsFAQAdvertise on SI
© 2026 Knight Sac Media.  Data provided by Twelve Data, Alpha Vantage, and CityFALCON News