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Biotech / Medical : Regeneron Pharmaceuticals
REGN 651.84+1.2%12:45 PM EST

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To: Miljenko Zuanic who wrote (3329)7/13/2021 2:07:40 AM
From: CuttingEdge Bio  Read Replies (1) of 3557
 
I am not sure which modality they will utilize, but I will note two things. Right now they have LepR agonist antibody in the clinic. LepR was also mentioned in this paper as one of the genetically validated common variant hits. I would expect perhaps a combo (multiple targets) approach is coming.
2. The recent deal with ALNY focused on its next-gen RNAi platform that specifically targets the CNS (and for the eye). If ALNY drug can get distributed to CNS where it needs to go and Abs can't, they will go with RNAi, and the profit sharing is not a relevant factor.
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