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Strategies & Market Trends : 2026 TeoTwawKi ... 2032 Darkest Interregnum
GLD 382.87-0.8%Nov 13 4:00 PM EST

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To: maceng2 who wrote (178164)9/12/2021 7:39:33 AM
From: TobagoJack5 Recommendations

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SirWalterRalegh
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Something else cropped up in in-tray



Chloroquine is a potent inhibitor of SARS coronavirus infection and spread (cdc.gov)

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Virology Journal volume 2, Article number: 69 (2005)

Conclusion:

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds

Other papers:

The anti-HIV-1 activity of chloroquine - PubMed (nih.gov)

Results: chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) are endowed with a broad anti-HIV-1 activity inhibiting X4, R5, and X4/R5 stains in lymphocytic and monocytic cells. Interestingly, CQ is capable of inhibiting HIV-1 replication at concentrations within the range reported in plasma of individuals chronically treated with doses of the drug which have well-known and limited toxicity. These effects have been confirmed in vivo in two clinical trials

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread (nih.gov)

Results

Preinfection chloroquine treatment renders Vero E6 cells refractory to SARS-CoV infection

Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeks (wiley.com)

Expanding the frontiers of existing antiviral drugs: Possible effects of HIV-1 protease inhibitors against SARS and avian influenza - ScienceDirect

Expanding the frontiers of existing antiviral drugs: Possible effects of HIV-1 protease inhibitors against SARS and avian influenza
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