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Biotech / Medical : Biotech Valuation
CRSP 56.58-0.7%3:59 PM EST
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To: A.J. Mullen who wrote (51929)2/1/2022 3:46:17 PM
From: Art Bechhoefer  Read Replies (1) of 52153
 
"Surely the important comparisons are effectiveness, safety, and side-effects?"

Absolutely! And even though 100 mg doesn't seem very large, the higher the dosage, the more likely to have safety or other problems. Remember as well that there can be interactions BETWEEN different drugs, which is especially applicable to us older people who take a lot of different medications.

And finally, which I didn't mention in the last post, the FDA lost a lot of credibility when it approved the BIIB drug that had shown little efficacy for many Alzheimer's patients. Denial of approval on drugs submitted later on was, it appears, partly a reaction to the FDA overruling its advisory committee and the subsequent resignations of many of those committee members. One can't be sure how the FDA will react either to the Madrigal or the Viking drugs. Just one more area of uncertainty.

Art
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