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Biotech / Medical : Depotech(depo)
DEPO 7.300+1.7%Aug 14 5:00 PM EST
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To: Jasman who wrote (718)2/11/1998 9:37:00 PM
From: John McCarthy  Read Replies (1) of 887
 
Jasman,

Sorry for the delay, got side tracked.
Please see if your memory jives with these numbers ...

I posted this way back when:

Regards,

John

The key line being Median Survival Rate:
========================================

---------------------------------------------------------------
Part 1 - Reconcile past ODAC meeting
---------------------------------------------------------------
ODAC VIEW OF DATA
------------------------------- ------- ------- ------
DepoCyt
Cytar- Metho-
abine trexate Total
------------------------------- ------- ------- ------
A A Total Population 31 30 61
B B Not Evaluable 0 0 0
------- ------- ------
C A - B Adj. Population 31 30 61
------- ------- ------
D D Responders 8 6 14
E E Responders Not Evaluable 0 0 0
------- ------- ------
F D - E Adj. Responders 8 6 14
------- ------- ------
G F/C % Responding 26 20 --
======= ======= ======

DEPO MANAGEMENT VIEW OF DATA
------------------------------- ------- ------- ------
DepoCyt
Cytar- Metho-
abine trexate Total
------------------------------- ------- ------- ------
A A Total Population 31 30 61
B B Not Evaluable 7 1 8
------- ------- ------
C A - B Adj. Population 24 29 53
------- ------- ------
D D Responders 8 6 14
E E Responders Not Evaluable 0 1 1
------- ------- ------
F D - E Adj. Responders 8 5 13
------- ------- ------
G F/C % Responding 33 17 --
======= ======= ======

Other Benchmarks cited DEPO News Releases:

Based on:
------- ------- ------
Adjusted Population 24 29 53
------- ------- ------
Benchmarks:

Median Survival Rate - Days 168 87
======= ======= ======
Disease Progresson - Days 108 48
======= ======= ======
Toxic Side Effects 69% Better %
======= ======= ======

Notes:

(1) DEPO Mgmt. REFUSES to explain the 7 people
they termed Not Evaluable.

(2) To steal a line from BIAO LUO - is DEPO Mgmt. CHERRY PICKING the
Control Population.

(3) (2) calls into question the VERACITY of DEPO Management.

(4) The WORST side effects occurred with Methotrexate usage.
1 Death and 1 CNS.

(5) Doctors who offered opinions on their review included
Richard Simon , Steve Hirschfeld , Sandra Swain and
Derek Ragavan.

(6) The final vote was 7 against and 3 for.
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