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Biotech / Medical : Biotech Valuation

CRSP 56.38

-9.0%

Nov 4 3:59 PM EST

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Lance Bredvold

OldAIMGuy

To: software salesperson who wrote (51997)	12/1/2022 3:02:47 PM
From: A.J. Mullen	2 Recommendations Read Replies (1) of 52153

Thanks for that. The trial results suggest lecanemab delays the onset of symptoms. There's no evidence of reversal and the author adds the effect was only significant at 18 months - not at 12. He sees the glass as half-empty. It looks like the delay is cumulative. The drug might make a substantial difference to a relatively young person newly diagnosed. The trial included people as young as 50, with many years left. The increased number of adverse effects in the drug arm of the trial is a concern. That's something for the FDA to chew on. At last, a drug has come out of treating amyloid plaques (or, in this case, a precursor). The Amyloid hypothesis was looking exhausted. Lecanemab will breath more life into it.

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