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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ)

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To: Jim who wrote (5553)2/20/1998 11:43:00 AM
From: Tunica Albuginea   of 23519
 
Jim, that is the news I had mentioned last week that I was getting from my colleagues. More and more of us are now
- going directly to 1000 mcg, if testing shows no low BP at 500;
skip the 500 mcg trial at home. 1000 is more effective.
-we noted that if any hypotension occurs it will occur at the lower
doses ( 500 ). A corollary is that, if NO hypotension occurs at
500, none will occur at 1000.
- Actis is always recommend now: keeps the pellet in the urethra
until completely dissolved. Always for ALL the drug to get into
the corpus cavernosum.It is removed when erection is full, prior
to sexual activity.
-there are several guys who are finding up to 70 -75% response with
the above method.
-the simple Axis method ( the band ) is a great and simple
discovery (as many discoveries are ). In the future, you'll be able to
put ALL kinds of ALREADY APPROVED drugs in the penis
with this technology.( There are all kinds of vasodilators that could
be used ).
-that would explain earlier lower response rates: i.e. they were due
to, use of low doses, the 250 and 500, non use of Axis, pellet
falling into bladder or other improper dispersal technique.
-we no longer define " sexual activity ".Recent events in Washington
have cast doubts as to what constitutes " proper sexual
activity". There have been some ( as yet unconfirmed ) reports that
some Washingtonians, ( at least 2 of them ) have undergone up to
37 testing visitations to try and determine what constitutes "
proper sexual activity ". So the Urologists I know, no longer
bother with that and we just give them the prescription with a
general indication, " to be used during sexual activity ".

TA
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