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Biotech / Medical : ImmunityBio converts from Immunomedics
IBRX 2.139+0.9%Nov 7 9:30 AM EST

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To: End2War who wrote (857)1/29/2025 3:39:27 PM
From: End2War   of 1230
 
Here is a further question I asked Chat GPT and its reply. Does anyone have any further thoughts on this issue of upcoming dilution, or do we think PSS is going to loan more money to IBRX to conduct the PH3 trial?

Question:

Does the strategic Partnership with BeiBene mean that they will be sharing the cost in some way of the PH3 trial, in effect, making this partnership a vehicle for IBRX to raise money to conduct the trials without needing to dilute?

ChatGPT said:



Yes, it is likely that ImmunityBio (IBRX) will share costs with BeiGene in some way for the Phase 3 trial, which could help mitigate the financial burden on IBRX and reduce the need for dilution. However, the press release does not explicitly state the financial terms of the collaboration, so the extent of BeiGene's financial contribution remains unclear.

Reasons Why BeiGene May Share Costs:
  1. Collaborative Supply Agreement:

    • The partnership is structured as a "collaboration and supply agreement," meaning BeiGene is providing its PD-1 checkpoint inhibitor, tislelizumab, as part of the study. This alone is a significant cost-sharing mechanism, as CPIs are expensive to manufacture and supply.
  2. Mutual Benefit in Expanding Market Reach:

    • BeiGene has a vested interest in expanding the indications for tislelizumab and gaining a foothold in the post-CPI NSCLC market. By supporting the trial, BeiGene could strengthen its presence in the U.S. and global markets, where competition among PD-1 inhibitors is fierce.
  3. ImmunityBio's Financial Constraints:

    • ImmunityBio has historically faced cash burn issues and funding challenges, making partnerships a strategic move to fund late-stage trials without issuing new shares. If BeiGene shares costs or provides funding, it could reduce the need for IBRX to raise capital through equity offerings, which often lead to stock dilution.
  4. BeiGene’s Financial Strength:

    • BeiGene, a much larger biotech company with a market cap of ~$16B, has more resources to invest in clinical development. It would make sense for BeiGene to co-fund the trial rather than let IBRX struggle with financial limitations that could delay or hinder trial execution.
Potential Implications for IBRX Investors:
  • Positive: If BeiGene is covering a substantial portion of the trial costs, it reduces IBRX's cash burn and delays or eliminates the need for a dilutive capital raise.
  • Neutral to Negative: If BeiGene is only providing the drug supply and not funding operational costs (e.g., site management, patient recruitment), then IBRX may still need to secure funding separately, potentially leading to dilution.
Key Takeaway:
  • If BeiGene is significantly contributing to costs, this partnership serves as a way for IBRX to advance its pipeline without raising money through equity sales.
  • If BeiGene's contribution is limited to drug supply, IBRX may still need to find alternative funding for operational costs.
  • Further details from SEC filings or company disclosures will be needed to confirm the financial structure of the partnership. Would you like me to check for recent filings related to this deal?
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