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Pastimes : Geeky and Nerdy
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From: Sun Tzu6/29/2025 10:09:46 AM
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Parkinson may be a kidney disease

"Led by a team from Wuhan University in China, the study is primarily concerned with the alpha-synuclein (a-Syn) protein, which is closely associated with Parkinson's. When production goes awry and creates clumps of misfolded proteins, it interferes with brain function.

The key discovery here is that a-Syn clumps can build up in the kidneys, as well as the brain. The researchers think these abnormal proteins might actually travel from the kidneys to the brain, possibly playing a part in triggering the disease.

"We demonstrate that the kidney is a peripheral organ that serves as an origin of pathological a-Syn," write the researchers in their published paper."
sciencealert.com.
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